Regulating General Mutation Rates: Examination of the Hypermutable State Model for Cairnsian Adaptive Mutation
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چکیده
منابع مشابه
Regulating general mutation rates: examination of the hypermutable state model for Cairnsian adaptive mutation.
In the lac adaptive mutation system of Cairns, selected mutant colonies but not unselected mutant types appear to arise from a nongrowing population of Escherichia coli. The general mutagenesis suffered by the selected mutants has been interpreted as support for the idea that E. coli possesses an evolved (and therefore beneficial) mechanism that increases the mutation rate in response to stress...
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ژورنال
عنوان ژورنال: Genetics
سال: 2003
ISSN: 1943-2631
DOI: 10.1093/genetics/163.4.1483